Pulmonary hyalinizing granuloma

Abstract

Pulmonary hyalinizing granuloma (PHG) first described by Engleman et al. in 1977, was generally reported as individual cases in the world literature.1 In most cases, PHG occurs as solitary or multiple pulmonary nodules with well defined boundaries.2 They usually grow slowly or may not grow at all; Although positron emission tomography CT is useful in ruling out metastatic lesions, increased metabolic activity may occur in PHG lesions.3 In histolog- ical analysis, homogeneous hyaline lamellae are usually detected in a perivascular distribution, surrounded by the collection of plasma cells, lymphocytes and histiocytes.