Effect of endometriosis on obstetric outcomes: A tertiary center experience

Abstract

Objective: The aim of this study is to compare the course of pregnancy in women with and without endometriosis for obstetric complications. Material and Methods: Patients applied to Istanbul University-Cerrahpasa were included in the case group, 49 patients in the control group, and evaluated retrospectively. Early and late pregnancy complications were recorded. P<0.05 was considered statistically significant. Results: A decrease in the rate of spontaneous pregnancy and a significant increase in the IVF rate were observed in the endometriosis group (p<0.05). Gestational hypertension,placental abruption, placental adhesion anomalies,premature rupture of membranes, fetal growth restriction, threat of preterm birth and oligohydramnios there was no significant difference between the two groups (p> 0.05). The rate of cesarean delivery was 55.1% in the control group and 61.0% in the endometriosis group (p>0.05). Postpartum uterine atony, bladder injury during cesarean section and requirement of postpartum blood transfusion seen in 6 (6.7%), 2(1.1%), and 1 (11.1%) patients respectively (p<0.05). Neonatal intensive care unit requirement was 39.0% and 24.4% in case and control group (p>0.05). Conclusion: Women with endometriosis are at higher risk for complications during pregnancy. The rates of miscarriage in the early gestational weeks, preeclampsia, placenta previa, gestational diabetes mellitus in the second and third trimesters, postpartum uterine atony, blood transfusion requirement,and surgical complications during cesarean section are higher in women with endometriosis.