Relation between visual acuity, macular retinal thickness, visual field and multifocal electroretinography in patients with retinitis pigmentosa

Abstract

Purpose: To investigate the correlation between corrected visual acuity (CVA), macular retinal thickness, visual fi eld and multifocal electroretinography (mfERG) responses in patients with retinitis pigmentosa (RP). Materials and Methods: The study included RP patients who were admitted to our clinic between January 2014 and December 2018 and had CVA at least ?0.05. All patients underwent thorough ophthalmologic examination. Spectral domain (SD) optical coherence tomography (OCT) was performed to assess macular retinal thickness and standard central 30-2 threshold test was used as visual fi eld test. The visual fi eld responses, matching to mfERG, were estimated by calculating average value for 5 concentric rings. Correlation analysis was performed among CVA, macular retinal thickness, visual fi eld and mfERG responses. Results: Forty-four eyes of 22 patients were included in the study. The mean age was 30.6±13.0 (range 17 to 52) years in the study population. The CVA ranged from 0.05 to 1. In our study, there was a positive correlation between CVA, macular retinal thickness (r=0.668, p<0.01), visual fi eld (r=0.578, p<0.01) and mfERG responses for ring 1 (r=0.511, p<0.01). Conclusion: In addition to ophthalmologic examination, visual fi eld, SD-OCT and mfERG are important tests in the follow-up of patients with RP. We think that ophthalmologic examination together with anatomical and functional tests will be useful in the clinical follow-up of these patients.