Investigation of possible effect of carnosic acid (CA) on combined exposure to bisphenol a (BPA) and diethyl hexyl phthalate (DEHP)

Abstract

DEHP and BPA, the main components of plastic products, are the important endocrine-disrupting chemicals which can mimic or disrupt the actions of estrogen by inhibiting normal functions of the body. Because of this widespread usage of DEHP and BPA, not only alone exposure but also combined exposure is considered as an important issue. Nowadays, researches are increased related to the effects on neurological functions instead of endocrine disrupting effects. This study aims to investigate combined exposure of DEHP and BPA and the possible effect of carnosic acid as an antioxidant.