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Biological activity and chemical composition of the essential oil from the fruits of Ferula rigidula Fisch. ex DC.

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dc.authorid0000-0003-2533-5141
dc.contributor.authorİşcan, Gökalp
dc.contributor.authorKürkçüoğlu, Mine
dc.contributor.authorTosun, Fatma
dc.contributor.authorMiski, Mahmut
dc.date.accessioned2023-08-11T12:26:16Z
dc.date.available2023-08-11T12:26:16Z
dc.date.issued2023
dc.departmentİstanbul Medipol Üniversitesi, Eczacılık Fakültesi, Eczacılık Meslek Bilimleri Bölümü, Farmakognozi Ana Bilim Dalı
dc.description.abstractThe hydro-distilled essential oils of the fruits of F. rigidula Fisch. ex DC. was analyzed by Gas Chromatography (GC) and Gas Chromatography/Mass Spectrometry (GC/MS) systems at the same time. Thirty-one compounds were characterized rep-resenting 98.2% of the essential oils. The main components of the oil were determined as a-pinene and camphene (24% and 20%, respectively). The anticandidal and antibacterial effects of the essential oil were determined by using partly modi-fied CLSI protocols M27-A2 and M7-A7, respectively. The essential oil of the dried fruits showed several inhibitory effects on the tested bacteria panel (MIC, 62.5 to 2000 µg/mL) and Candida species (MIC, 125 to 1000 µg/mL).
dc.identifier.citationİşcan, G., Kürkçüoğlu, M., Tosun, F. ve Miski, M. (2023). Biological activity and chemical composition of the essential oil from the fruits of Ferula rigidula Fisch. ex DC. Acta Pharmaceutica Sciencia, 61(3), 257-268. https://dx.doi.org/10.23893/1307-2080.APS6117
dc.identifier.doi10.23893/1307-2080.APS6117
dc.identifier.endpage268
dc.identifier.issn1307-2080
dc.identifier.issue3
dc.identifier.scopus2-s2.0-85166001094
dc.identifier.scopusqualityQ3
dc.identifier.startpage257
dc.identifier.urihttps://dx.doi.org/10.23893/1307-2080.APS6117
dc.identifier.urihttps://hdl.handle.net/20.500.12511/11312
dc.identifier.volume61
dc.indekslendigikaynakScopus
dc.institutionauthorTosun, Fatma
dc.language.isoen
dc.publisherIstanbul Medipol University
dc.relation.ispartofActa Pharmaceutica Scienciaen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı
dc.rightsinfo:eu-repo/semantics/openAccess
dc.subjectAntibacterial
dc.subjectAnticandidal
dc.subjectFerula Rigidula
dc.subjectEssential Oil
dc.subjectGCMS
dc.titleBiological activity and chemical composition of the essential oil from the fruits of Ferula rigidula Fisch. ex DC.
dc.typeArticle

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