The relationship between vitamin d levels and cardiovascular risk scores in geriatric patients with type 2 diabetes mellitus

Abstract

Objective: The aim of this study is to evaluate the relationship between vitamin D levels and various cardiovascular risk scoring systems such as QRISK2, BNF, ASSING, SCORE and Framingham in geriatric diabetic patients. Methods: 60 diabetic geriatric patients with vitamin D deficiency (10–30 ng/mL) and 40 geriatric patients with vitamin D deficiency (<10 ng/mL) were included in the study. The scores of the patients indicating cardiovascular disease risks such as QRISK2, BNF, ASSIGN, SCORE and Framingham were calculated. All values were compared between these two groups. Results: While the Framingham risk score (p<0.001), BNF (p=0.001) and SCORE (p<0.001) were found to be significantly higher in patients with vitamin D deficiency, other scores did not significantly differ between the groups. There was a weak but statistically significant neg- ative correlation between 25[OH] D levels with Framingham risk score (p<0.001 r=-0.384), BNF score (p=0.003 r=-0.299), and Score score (p=<0.001 r=-0.407). Conclusion: In the present study, we found a close relationship between the Framingham, BNF and ASSIGN cardiovascular risk score and serum vitamin D concentrations in diabetic geriatric patients.